The correctly chosen and properly operating Oxygen Supply System is one of the most mportant requirements for safe and efficient ozone therapy.
Oxygen gas can be supplied to Medical Ozone Generators of Medozons series from central oxygen network or oxygen tank. As oxygen source can also be used an oxygen concentrator or electrochemical generator of oxygen. For proper function of Medical Ozone Generators of Medozons series the Oxygen Supply System should be equipped with an Oxygen Pressure Regulator adjustable from 0,3 to 1,5 bar (atm).
Oxygen Extra Purification Filter
Oxygen used in practice may contain micro-quantities of technical oils, moisture etc, thus extra purification of oxygen through a built-in carbon filter at the oxygen inlet port of ozone generator can be of great importance.
The filter used in Medical Ozone Generators of Medozons series ensures rough and fine purification of oxygen as well as its drying, and the ozonization chamber receives therefore guaranteed pure oxygen.
Autonomous Oxygen Supply System (as an example)
Designed for delivering medical oxygen of required quality to Medical Ozone Generators of Medozons series.
The system includes
2L flask, handle/stand, pressure reducer, flow regulator, manometer. The system is equipped with an adapter for oxygen filling from an external flask and a clamp for fixation of oxygen hose.
The system includes: 2L flask, handle/stand, pressure reducer, flow regulator, manometer. The system is equipped with an adapter for oxygen filling from an external flask and a clamp for fixation of oxygen hose.
The reducer is adjusted for proper work pressure of Medical Ozone Generators of Medozons series and constant oxygen flow-rate of 0,5 L/min and does not require any additional regulation.
Medical Ozone Generators of Medozons series supplied with oxygen from this system should be operated at ozone/oxygen flow-rate of 0,25 or 0,5 Liter per minute.
How to Fill the Autonomous Oxygen Supply System
In spite of simple filling procedure, it should be done by a technician familiar with the safety requirements for use of pressurized vessels.
To fill the autonomous oxygen supply system use the adapter. For assembly use paronit insertions.
Remove the plug and fasten the adapter. Make sure that the valve of the system is closed.
Fasten the adapter onto a 40L oxygen flask, using a spanner tighten thread connections.
First open the valve of the oxygen system, then the valve of the big flask. Oxygen is conveyed from the flask to the oxygen system. The filling process is finished after whistle of "conveying" oxygen has stopped. Close the valve of the big flask, then the valve of the oxygen system. Disconnect the adapter.
Install the manometer (do not forget the insertion). The manometer shows residual oxygen pressure in the flask.
Connect the oxygen hose to the outlet of the oxygen system, use a PVC tube with diameter 6mm included into the connection set of each ozone generator of Medozons series, fix the connection with the clamp.
Connect the other end of the oxygen hose to the inlet of the ozone generator. The work place of ozone therapy practitioner is ready.
For oxygen delivery open the valve of the oxygen system.
The work place of ozone therapy practitioner, fitted out with the autonomous oxygen supply system.
The valve of the oxygen supply system should be opened for 2-3 minutes before work to make sure that the gas supply system of the ozone generator is filled with oxygen.
Rotation of colored parts of the reducer is forbidden because this can result in disturbances of regulation made by the manufacturer and failure of the unit.
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You've brought up the problem of toxic impurities possibly containing in the delivered ozone/oxygen mixture. Is it really so important?
Every doctor using ozone therapy must be sure of its safety, thus there must be no doubt about the purity of delivered ozone/oxygen gas mixtures for medical use (they should be contaminant-free).
We consider this problem as very important. It is a fact that after approx. 100 hours of continuous operation owing to the electrochemical erosion of the ozonization chamber walls and electrodes some of available ozone generators deliver an ozone/oxygen gas mixture contaminated by impurities (calcium, aluminium, silicon, magnesium, copper etc) in concentrations considered as dangerous for the health that however can become evident even some months or years after the treatment. This claim is valid through the investigation of the upper layer taken from the ozonization chamber wall. There are only two possible reasons for the products which were found out on the wall:
Destruction of the electrodes (the discovered products are equivalent to the materials of electrodes);
Fine contaminants possibly containing in oxygen which during the ozonolysis can be converted into toxic products.
A decrease in the ozone production can be considered as a starting point for destruction of the ozonization chamber wall (after approx. 100 hours of continuous operation). The so-called "traditional" ozone generators should be used very carefully, particularly for parenteral ozone therapy in the form of intravenous infusions of ozonated saline that can serve as ideal medium for fine contaminants.
Parenteral methods of ozone therapy are safe only if the ozone generator delivers pure contaminant-free medical ozone. Each medical ozone generator should be equipped with a filter for extra purification of oxygen used; purity of delivered ozone/oxygen gas mixtures should be guaranteed by the manufacturer through available test protocols, the same is about accuracy in maintaining the chosen ozone concentration (not worse than 10%) and great operation resource (durability) of ozonization chamber (without any decrease in the ozone production and without any change in ozone concentration accuracy) for at least 2000 hours of continuous operation.
What do you think about oxygen concentrators used as Oxygen Supply Systems for medical ozone generators?
There is no definite opinion at this point. Oxygen produced by these devices very seldom reaches the purity of 95% and higher, and we don not know whether the remaining 5% of content would not be dangerous due to electric synthesis in the ozonization chamber or interaction with ozone.
As you know, medical ozone generators require the use of medical oxygen referred to oxygen gas with guaranteed purity of 99,9% and higher. Anyways, we do not mind the use of oxygen concentrators for external i.e. local methods of ozone therapy.
Would you please explain a necessity for a built-in oxygen filter in medical ozone generators?
Our previous experience has shown that oxygen used can contain micro-quantities of technical oils, thus each ozone generator intended for medical use should be equipped with a filter for extra purification of oxygen that inhibits the introduction of technical oils possibly containing in oxygen into the ozonization chamber. During the ozonolysis technical oils can be converted into dangerous toxic products (fatty acids, ketones, aldehydes etc).
Within a long operation time of ozone generator great volumes of oxygen are conveyed through the ozonization chamber (within 100 hours of operation in case of saline ozonization at a flow-rate of 1 L/min approx. 6000 L of oxygen are conveyed through the ozonization chamber), the ozonization chamber gradually becomes covered with an oily layer, and the doctor cannot be sure of the quality of gas mixtures delivered, thus extra purification of oxygen through a filter at the inlet of ozone generator is a reasonable step.
Would you please explain the parameter "Range of selecting the dose of ozone"?
It is puzzling to us that some manufacturers of medical ozone generators use the parameter "Ozone production per 1 hour". This parameter was obviously taken from the ozone technology for water treatment, but in the medicine the ozone production should be adjustable at least per 1 min
How important is the accuracy of +/-5% … +/-10% in maintaining the chosen ozone concentration and the adjustable range 1 : 9950, as far as I know, recently these parameters have not been taken into consideration?
Before the New-Generation of medical ozone machines characterized by unique accuracy in maintaining the chosen ozone concentration and a uniquely wide range of ozone concentration adjustment, the doctors using ozone therapy were conditioned by the "traditional" types of ozone generator with very low accuracy in maintaining the chosen ozone concentration (worse than 40-50% as a rule) and a narrow adjustable range (1 : 15 - from 1 mg/l to 15 mg/l). The ozone concentration accuracy of +/-5% …+/-10% ensures a reasonable, predictable and dose-related therapy.
The high accuracy in maintaining the chosen ozone concentration allows using ozone like any other generally accepted medicine. That might have been one of the obstacles for wide spreading of ozone therapy. Nevertheless, all advantages of the Medozons machine do not influence its price, but this is a fact that there are many medical ozone generators on the market being much more expensive, but inferior in technical properties as compared with our machines.
The parameters "Range of ozone concentration adjustment 1:9950" and "Range of selecting the dose of ozone 0,25 … 10000" are not clear to us.
Would you please explain it?
We can explain it with the Medozons-BM:
Range of delivered ozone concentrations (50…10 000) mcg/L. This parameter means that the machine is able to maintain the chosen ozone concentration within the available range with accuracy not worse than +/- 10%: 107 mcg/L or 5671 mcg/L.
The parameter "Range of ozone concentration adjustment (1 : 9950)" means that the machine is able to provide 9950 values/gradations of ozone concentration with accuracy +/-10% that characterizes the depth of adjustment.
The range of selecting the dose of ozone characterizes a wide range of ozone dosage adjustment from 0,25 mcg/L to 10000 mcg/L with accuracy +/-5%, at an ozone/oxygen flow-rate of 0,25 L/min adjustable by step 0,25 mcg; 0,5 L/min - 0,5 mcg; 1 L/min - 1 mcg.
So, medical ozone generators of Medozons series are able to produce guaranteed pure medical ozone and dose it exactly, with regards to technical and medical features they are the best ones within Russia and have no analogies worldwide! We are sure that the above parameters today considered as unique tomorrow will be the new standards of ozone therapy.
Would you please explain a necessity for an automated system of ozone-oxygen flow-rate adjustment, what about doing it manually by means of oxygen flow regulator? The use of fixed flow-rates (0,25; 0,5; 1,0 L/min) may limit the range of ozone applications.
Manually setting of oxygen flow-rate by means of regulator may induce a considerable decrease in ozone dosage accuracy (the dose of ozone = CO3 x O2/O3 flow-rate x treatment time) due to possible oxygen pressure fluctuations (in oxygen tank or any other oxygen supply system) or any change in gas tract resistance.
In medical ozone generators of Medozons series oxygen flow-rate delivered to the ozonization chamber is automatically stabilized at the given level regardless of influence from outside, the automated stabilization system of oxygen flow-rate is reliable even in case of considerable pressure fluctuations that ensures a dose-related therapy. The automatic gas supply system is tested by the manufacturer for accuracy in maintaining the chosen oxygen flow-rate. We are convinced that the fixed O2/O3 flow-rates do not limit, but widen the range of ozone applications, most of doctors perform ozone therapy at a flow-rate of 1 L/min, but using a flow-rate of 0,5 or 0,25 L/min it is possible to successfully perform intracavitary ozone therapy (in gynecology, urology etc).
How would you explain the fact that your ozone generators are not equipped with a measuring device to determine the delivered ozone concentration? To my mind, this can discredit the method of ozone therapy. From my own experience I know that at the starting point any medical ozone generator has the actual accuracy of delivered ozone concentration +/-40…+/-80%.
In medical ozone generators of Medozons series like Medozons-BM and BM-02 you can see a different functional principle of the ozonization chamber that ensures a wide range of ozone concentration adjustment (from 50 to 10000 mcg/L) with high accuracy in automatically maintaining the chosen ozone concentration not worse than +/- 10%, in fact, the actual accuracy tested by the manufacturer is not worse than +/- 5%. The attested accuracy is valid for at least the same time as the specified durability of the ozonization chamber before the scheduled prophylactic service (2000 hours of continuous operation or about 5 years of usage). The latest device Medozons-System has a built-in measurer of ozone concentratrions.
N.B. The information on our website is intended for medical professionals, since ozone therapy and medical ozone generators should be used in a clinical setting under the supervision of a medical doctor.