Equipment and Accessories for Modern High-Effective Technology of Ozone Therapy and Ozone prophylaxis
Equipment and Accessories for Modern High-Effective Technology of Ozone Therapy and Ozone prophylaxis
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Methods of Ozone Therapy
Basic Procedures of Systemic Action
1. Major Autohaemotherapy (AHT) with ozone.
One of the most effective methods of systemic action. During this procedure a certain volume of the patient's whole blood is withdrawn from the cubital vein by means of a disposable infusion set, enriched with an ozone/oxygen gas mixture (O2/O3) in a plastic container called Haemokon (the O2/O3 is introduced into the container before withdrawal of blood) or in a sterile glass bottle after isotonic NaCl solution (in this case the O2/O3 is introduced into the bottle after withdrawal of blood).
The bottle contains 100 ml of remained NaCl solution mixed with heparin. The treated blood containing active forms of oxygen (ozonides) is reinfused to the patient through the same infusion set.
The picture below demonstrates the variant of this procedure with a Haemokon and a 3- or 4-way-faucet.
The picture below demonstrates the variant of this procedure with a Haemokon and a 3- or 4-way-faucet.
- Put the accessories together. To a 3-way-faucet attach a venous puncture needle or catheter, syringe and infusion set, the latter is connected with a Heamokon or sterile bottle after isotonic NaCl solution.
- Introduce into the Haemokon the O2/O3 of the known volume (100-200 ml at ozone concentration 3000-10000 mcg/L), make a venous puncture.
- By manipulation with the 3-way-faucet and syringe take into the Haemokon 50-150 ml of blood. By getting on the walls to the Haemokon placed below the level of vein, owing to a large exchange area the blood immediately reacts with ozone and becomes light red.
- By manipulation with the 3-way-faucet and syringe infuse the blood by flow way to the vein.
- This manipulation can be repeated several times to treat a larger volume of blood.
This procedure can be carried out without a 3-way-faucet if the blood is withdrawn by self-flow through a disposable infusion set and reinfused drop-by-drop when the Haemokon or bottle is hanging over a transfusion stand.
2. Minor Autohaemotherapy (AHT) with ozone
is a traditional method of immunostimulation.
O2/O3 is introduced into one syringe, and blood from the vein is taken into another syringe, then carefully transferred into the syringe with O2/O3. The blood enriched with ozone is administered intramuscularly into the buttock.
O2/O3 is introduced into one syringe, and blood from the vein is taken into another syringe, then carefully transferred into the syringe with O2/O3. The blood enriched with ozone is administered intramuscularly into the buttock.
3. Extracorporeal (continuous-flow) treatment of large volume autoblood (EBOO or RHP).
Low ozone concentrations, long time of treatment. The most difficult and at the same time the most effective method of systemic action.
4. Parenteral infusion of ozonated physiological saline solution.
Headliner of Russian approach of ozone therapy. Can be used in ambulatory conditions. The most frequently used procedure.
5. Rectal ozone insufflations
can be considered as an alternative to parenteral methods of ozone therapy, noninvasive, able to provide a systemic effect on the human body through fast resorption of ozone by rectum mucosa and conveying into the blood bed.
Can be carried out with a Janet's syringe or special plastic container (the Medozons-Set, Order-No. 30\01) connected with a disposable rectal catheter.
Basic Procedures of Local Action
1. Treatment of pathological processes with ozone/oxygen gas mixtures in plastic chambers or frame-chambers (bagging) under high or low pressure or alternating between high and low pressure.
O2/O3 flow-rate - 1 L/min, СО3 = 10000 … 2000 mcg/L, Pressure\low pressure - + 0,1 … + 1,0, -0,1 … -0,7 atm, removal rate - 0 … 5 L\min
2. Treatment of pathological processes on small body areas with ozone/oxygen gas mixtures by means of "suction cup" in low pressure conditions.
O2/O3 flow-rate - 1 L\min, СО3 = 10000 … 2000 mcg\L, Low pressure - 0,2 … 0,7 atm, removal rate - 2 … 5 L\min
3. Continuous-flow intravaginal insufflations of ozone/oxygen gas mixtures.
4. Continuous-flow intravaginal instillations of ozonized water fine dispersions.
4. Continuous-flow intravaginal instillations of ozonized water fine dispersions.
The exhaust O2/O3 is evacuated by producing with a pumping unit the so-called "air barrage" (without pressure and low pressure) that helps to remove the exhaust O2/O3 to a destructor.
5. Local ozone baths in plastic chambers with bubble hydromassage.
The picture demonstrates the frame-chamber "shank" (Order-No. 21\01). Effective for different kinds of trophic disorders. The damaged area is placed in the flow of rising O2/O3 bubbles. Several factors are working here at the same time – the combined action of gaseous and fluid phases + light massage with bubbles that increases the treatment effectiveness.
6. Vacuum-vibratory massage with ozonized olive oil.
Vibration frequency 0,5 - 2 Hz.
Most frequently used in cosmetology for anti-cellulite treatment programs.
Most frequently used in cosmetology for anti-cellulite treatment programs.
7. Ozone injections of different kind:
intramuscularly, intra- or periarticularly, subcutaneously, intracutaneously, paravertebrally, intravascularly. Subcutaneous injections can also be performed by means of a multi-injector (the so-called "comb") connected via tubing with 5 standard 30 gauge needles.
The flow-rate of gas mixture is 2-3 ml/min through each needle. This method is used in the treatment of large body areas damaged by cellulite and local lipodystrophy.
Ozone Therapy
In Different Fields Of Medicine
In Different Fields Of Medicine
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FAQ
You've brought up the problem of toxic impurities possibly containing in the delivered ozone/oxygen mixture. Is it really so important?
Every doctor using ozone therapy must be sure of its safety, thus there must be no doubt about the purity of delivered ozone/oxygen gas mixtures for medical use (they should be contaminant-free).
We consider this problem as very important. It is a fact that after approx. 100 hours of continuous operation owing to the electrochemical erosion of the ozonization chamber walls and electrodes some of available ozone generators deliver an ozone/oxygen gas mixture contaminated by impurities (calcium, aluminium, silicon, magnesium, copper etc) in concentrations considered as dangerous for the health that however can become evident even some months or years after the treatment. This claim is valid through the investigation of the upper layer taken from the ozonization chamber wall. There are only two possible reasons for the products which were found out on the wall:
Parenteral methods of ozone therapy are safe only if the ozone generator delivers pure contaminant-free medical ozone. Each medical ozone generator should be equipped with a filter for extra purification of oxygen used; purity of delivered ozone/oxygen gas mixtures should be guaranteed by the manufacturer through available test protocols, the same is about accuracy in maintaining the chosen ozone concentration (not worse than 10%) and great operation resource (durability) of ozonization chamber (without any decrease in the ozone production and without any change in ozone concentration accuracy) for at least 2000 hours of continuous operation.
We consider this problem as very important. It is a fact that after approx. 100 hours of continuous operation owing to the electrochemical erosion of the ozonization chamber walls and electrodes some of available ozone generators deliver an ozone/oxygen gas mixture contaminated by impurities (calcium, aluminium, silicon, magnesium, copper etc) in concentrations considered as dangerous for the health that however can become evident even some months or years after the treatment. This claim is valid through the investigation of the upper layer taken from the ozonization chamber wall. There are only two possible reasons for the products which were found out on the wall:
- Destruction of the electrodes (the discovered products are equivalent to the materials of electrodes);
- Fine contaminants possibly containing in oxygen which during the ozonolysis can be converted into toxic products.
Parenteral methods of ozone therapy are safe only if the ozone generator delivers pure contaminant-free medical ozone. Each medical ozone generator should be equipped with a filter for extra purification of oxygen used; purity of delivered ozone/oxygen gas mixtures should be guaranteed by the manufacturer through available test protocols, the same is about accuracy in maintaining the chosen ozone concentration (not worse than 10%) and great operation resource (durability) of ozonization chamber (without any decrease in the ozone production and without any change in ozone concentration accuracy) for at least 2000 hours of continuous operation.
What do you think about oxygen concentrators used as Oxygen Supply Systems for medical ozone generators?
There is no definite opinion at this point. Oxygen produced by these devices very seldom reaches the purity of 95% and higher, and we don not know whether the remaining 5% of content would not be dangerous due to electric synthesis in the ozonization chamber or interaction with ozone.
As you know, medical ozone generators require the use of medical oxygen referred to oxygen gas with guaranteed purity of 99,9% and higher. Anyways, we do not mind the use of oxygen concentrators for external i.e. local methods of ozone therapy.
As you know, medical ozone generators require the use of medical oxygen referred to oxygen gas with guaranteed purity of 99,9% and higher. Anyways, we do not mind the use of oxygen concentrators for external i.e. local methods of ozone therapy.
Would you please explain a necessity for a built-in oxygen filter in medical ozone generators?
Our previous experience has shown that oxygen used can contain micro-quantities of technical oils, thus each ozone generator intended for medical use should be equipped with a filter for extra purification of oxygen that inhibits the introduction of technical oils possibly containing in oxygen into the ozonization chamber. During the ozonolysis technical oils can be converted into dangerous toxic products (fatty acids, ketones, aldehydes etc).
Within a long operation time of ozone generator great volumes of oxygen are conveyed through the ozonization chamber (within 100 hours of operation in case of saline ozonization at a flow-rate of 1 L/min approx. 6000 L of oxygen are conveyed through the ozonization chamber), the ozonization chamber gradually becomes covered with an oily layer, and the doctor cannot be sure of the quality of gas mixtures delivered, thus extra purification of oxygen through a filter at the inlet of ozone generator is a reasonable step.
Within a long operation time of ozone generator great volumes of oxygen are conveyed through the ozonization chamber (within 100 hours of operation in case of saline ozonization at a flow-rate of 1 L/min approx. 6000 L of oxygen are conveyed through the ozonization chamber), the ozonization chamber gradually becomes covered with an oily layer, and the doctor cannot be sure of the quality of gas mixtures delivered, thus extra purification of oxygen through a filter at the inlet of ozone generator is a reasonable step.
Would you please explain the parameter "Range of selecting the dose of ozone"?
It is puzzling to us that some manufacturers of medical ozone generators use the parameter "Ozone production per 1 hour". This parameter was obviously taken from the ozone technology for water treatment, but in the medicine the ozone production should be adjustable at least per 1 min
How important is the accuracy of +/-5% … +/-10% in maintaining the chosen ozone concentration and the adjustable range 1 : 9950, as far as I know, recently these parameters have not been taken into consideration?
Before the New-Generation of medical ozone machines characterized by unique accuracy in maintaining the chosen ozone concentration and a uniquely wide range of ozone concentration adjustment, the doctors using ozone therapy were conditioned by the "traditional" types of ozone generator with very low accuracy in maintaining the chosen ozone concentration (worse than 40-50% as a rule) and a narrow adjustable range (1 : 15 - from 1 mg/l to 15 mg/l). The ozone concentration accuracy of +/-5% …+/-10% ensures a reasonable, predictable and dose-related therapy.
The high accuracy in maintaining the chosen ozone concentration allows using ozone like any other generally accepted medicine. That might have been one of the obstacles for wide spreading of ozone therapy. Nevertheless, all advantages of the Medozons machine do not influence its price, but this is a fact that there are many medical ozone generators on the market being much more expensive, but inferior in technical properties as compared with our machines.
The high accuracy in maintaining the chosen ozone concentration allows using ozone like any other generally accepted medicine. That might have been one of the obstacles for wide spreading of ozone therapy. Nevertheless, all advantages of the Medozons machine do not influence its price, but this is a fact that there are many medical ozone generators on the market being much more expensive, but inferior in technical properties as compared with our machines.
The parameters "Range of ozone concentration adjustment 1:9950" and "Range of selecting the dose of ozone 0,25 … 10000" are not clear to us.
Would you please explain it?
Would you please explain it?
We can explain it with the Medozons-BM:
So, medical ozone generators of Medozons series are able to produce guaranteed pure medical ozone and dose it exactly, with regards to technical and medical features they are the best ones within Russia and have no analogies worldwide! We are sure that the above parameters today considered as unique tomorrow will be the new standards of ozone therapy.
- Range of delivered ozone concentrations (50…10 000) mcg/L. This parameter means that the machine is able to maintain the chosen ozone concentration within the available range with accuracy not worse than +/- 10%: 107 mcg/L or 5671 mcg/L.
- The parameter "Range of ozone concentration adjustment (1 : 9950)" means that the machine is able to provide 9950 values/gradations of ozone concentration with accuracy +/-10% that characterizes the depth of adjustment.
- The range of selecting the dose of ozone characterizes a wide range of ozone dosage adjustment from 0,25 mcg/L to 10000 mcg/L with accuracy +/-5%, at an ozone/oxygen flow-rate of 0,25 L/min adjustable by step 0,25 mcg; 0,5 L/min - 0,5 mcg; 1 L/min - 1 mcg.
So, medical ozone generators of Medozons series are able to produce guaranteed pure medical ozone and dose it exactly, with regards to technical and medical features they are the best ones within Russia and have no analogies worldwide! We are sure that the above parameters today considered as unique tomorrow will be the new standards of ozone therapy.
Would you please explain a necessity for an automated system of ozone-oxygen flow-rate adjustment, what about doing it manually by means of oxygen flow regulator? The use of fixed flow-rates (0,25; 0,5; 1,0 L/min) may limit the range of ozone applications.
Manually setting of oxygen flow-rate by means of regulator may induce a considerable decrease in ozone dosage accuracy (the dose of ozone = CO3 x O2/O3 flow-rate x treatment time) due to possible oxygen pressure fluctuations (in oxygen tank or any other oxygen supply system) or any change in gas tract resistance.
In medical ozone generators of Medozons series oxygen flow-rate delivered to the ozonization chamber is automatically stabilized at the given level regardless of influence from outside, the automated stabilization system of oxygen flow-rate is reliable even in case of considerable pressure fluctuations that ensures a dose-related therapy. The automatic gas supply system is tested by the manufacturer for accuracy in maintaining the chosen oxygen flow-rate. We are convinced that the fixed O2/O3 flow-rates do not limit, but widen the range of ozone applications, most of doctors perform ozone therapy at a flow-rate of 1 L/min, but using a flow-rate of 0,5 or 0,25 L/min it is possible to successfully perform intracavitary ozone therapy (in gynecology, urology etc).
In medical ozone generators of Medozons series oxygen flow-rate delivered to the ozonization chamber is automatically stabilized at the given level regardless of influence from outside, the automated stabilization system of oxygen flow-rate is reliable even in case of considerable pressure fluctuations that ensures a dose-related therapy. The automatic gas supply system is tested by the manufacturer for accuracy in maintaining the chosen oxygen flow-rate. We are convinced that the fixed O2/O3 flow-rates do not limit, but widen the range of ozone applications, most of doctors perform ozone therapy at a flow-rate of 1 L/min, but using a flow-rate of 0,5 or 0,25 L/min it is possible to successfully perform intracavitary ozone therapy (in gynecology, urology etc).
How would you explain the fact that your ozone generators are not equipped with a measuring device to determine the delivered ozone concentration? To my mind, this can discredit the method of ozone therapy. From my own experience I know that at the starting point any medical ozone generator has the actual accuracy of delivered ozone concentration +/-40…+/-80%.
In medical ozone generators of Medozons series like Medozons-BM and BM-02 you can see a different functional principle of the ozonization chamber that ensures a wide range of ozone concentration adjustment (from 50 to 10000 mcg/L) with high accuracy in automatically maintaining the chosen ozone concentration not worse than +/- 10%, in fact, the actual accuracy tested by the manufacturer is not worse than +/- 5%. The attested accuracy is valid for at least the same time as the specified durability of the ozonization chamber before the scheduled prophylactic service (2000 hours of continuous operation or about 5 years of usage). The latest device Medozons-System has a built-in measurer of ozone concentratrions.
© MEDOZONS Ltd., 2009
Ul. B.Panina 9 * 603089 Nizhny Novgorod / Russia
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