Worldwide the dose of ozone used for major AHT ranges from 500 to 3000 mcg of ozone, but during over 30 years' clinical experience our doctors very rarely used the dose higher 1000 mcg (only in exceptional cases like severe viral conditions to inactivate the virus at the primary stage, for example hepatitis, HIV, AIDS etc.). Besides, you should know that high doses of ozone must be used under strict control of anti- and prooxidant systems and if necessary in combination with antioxidant therapy to prevent an oxidative stress and fast exhaustion of antioxidant resource of the human body (increased production of free radicals and decreased efficacy of the antioxidant system inactivating them), so we recommend to use an appropriate control device like FRAS (Free-Radical Analytical System) or BChL (Program-Methodcal System for Biochemiluminescence Analysis). Besides, for chronic patients who every 3-6 months need to repeat a treatment course of ozone therapy it is very important to use low doses of ozone, primarily because it is proved that if the human body receives the maximum active dose of ozone at once, next time its reaction to the same dose will be less, but the therapeutically active and safe range of ozone therapy is limited that means with time ozone therapy will be less and less effective for such patients.
Prof. Peretyagin is absolutely convinced that if there is an approach allowing to achieve positive clinical effects in different diseases within a low range of ozone doses, this one should be a method of choice.
The priority of the Russian school of ozone therapy is the wide use of ozonated saline drips – a systemic method of ozone therapy considered as a genuine alternative to major autohaemotherapy and rectal ozone insufflations. For the patient this method provides comfort during the procedure, hygienic safety and better therapeutic effects. More and more doctors worldwide estimate the benefits of the Russian method: simple and patient-friendly performance, strictly dose-related therapy, excellent therapy hygiene (no risk of contamination). This method is based on much longer and gentle contact of ozone dissolved in physiological solution with the internal environment of the patient when ozone drop by drop, molecule by molecule is introduced into the blood circulation and immediately reacts with the blood components, so the whole blood quantity being in circulation comes into contact with ozone thus providing much better and prolonged therapeutic effects. Based on the use of considerably lower ozone concentrations this method yields normalization of oxidoreduction potential of the organism. In case of initial prooxidant shift characteristic of acute inflammatory diseases it activates the antioxidant defense system (AOD) therefore producing an anti-inflammatory effect, on the contrary, in case of initial hyperactivity of AOD characteristic of chronic, sluggish process ozone induces a prooxidant shift therefore decreasing the level of AOD. In case of MAHT it's necessary to use antioxidants to prevent suppression of AOD. More and more European doctors formerly specialized in major autohaemotherapy have changed to the Russian method.
We recommend using ozonated saline prepared with ozone concentrations (in gas phase) from 500 to 5000 mcg/L (0,5 to 5 mcg/ml). According to our technology (saturation with ozone concentrations 1000-3000 mcg/L) the patient receives 40-120 mcg of ozone in 200 ml of saline. For sick or healthy human body it does make difference how hard we "whip" its fermentative systems with oxidative "knout". According to our technology direct delivery of low doses of ozone into the blood flow leads to direct reactions between ozone as oxidant and biosubstrates of blood and secondary reactions through activation of enzymatic systems, synthesis modulation and release of numerous endogenous BAS.
The safety and efficiency of the Russian approach of ozone therapy is valid through scientific and clinical evidence in different fields of medicine.